José Antonio Rodríguez Piedrabuena -- Exercise and the brain
Regular physical exercise not only keeps those who engage in physical activity physically and mentally younger, with a longer life expectancy, but also improves cognitive performance and vitality. We know that holidays increase levels of dopamine and serotonin, which are essential for motivation, well-being and sleep. But, a […]
José Antonio Rodríguez Piedrabuena -- Exercise rejuvenates molecular programmes of ageing tissues
It is well known that physical exercise is beneficial to health, but there are little-known aspects that underline its importance, for example in rejuvenation. There is evidence that exercise reverses ageing-related gene changes and thus the phenotypes of senescence and chronic inflammation in the human body.
José Antonio R. Piedrabuena -- For animal lovers and all of us
It is clear how violent wild animals can be. But we have proof and you can see it in documentaries - on YouTube - where it is shown that love, in the form of care from birth, changes the brains of all of them and they become kind and loving companion animals. They, and we, develop [...]
José Antonio R. Piedrabuena -- The best recipe for getting old and ill
Accumulated evidence indicates an association between the circadian clock, the ageing process and metabolic stability. Our bodies, like everything else that is alive on the planet, are adjusted to the circadian rhythm. Television, going out partying, going to bed late are having serious consequences. This causes us to age very quickly, […]
José Antonio R. Piedrabuena -- Coping with the stressful effects of the pandemic
It is common to spend a lot of money on anti-ageing treatments, but the truth is that the only scientifically proven one is exercise. I have seen some people after six months and found them to have aged due to lack of exercise. Exercise has many beneficial effects on brain health, as it helps to reduce […]
José Antonio R. Piedrabuena -- Why do we need to exercise?
We are alive because all our organs communicate with each other through molecular signals, and we age when these signals decrease or encounter resistance, or fail to exit or have difficulty entering. Exercise stimulates communication between organs: skeletal muscle, heart, bones, liver, and adipose tissue, […]
José Antonio R. Piedrabuena -- Diet for our brain
Youth ends very early, and the deterioration begins imperceptibly, varying in its onset depending on lifestyle, diet, genetics and the environment in which they live. Polluted air not only affects the cardiorespiratory system but also the brain, making learning and memory difficult. Just like loud noise [...]
José Antonio R. Piedrabuena -- The only drug for the brain and ageing
El envejecimiento conduce a cambios funcionales en el hipocampo, una estructura cerebral que es fundamental para el aprendizaje, haciendo que la capacidad de aprender nuevas tareas disminuya con la edad. A nivel celular, se reducen los contactos sinápticos, la fuerza sináptica y la plasticidad, la neurogénesis del hipocampo disminuye con el envejecimiento, y los estudios […]
Endothelium, exercise and COVID-19
After being discharged, a person who has had COVID-19 is readmitted a month later for multiple thromboses in the legs and lung. He suffers from a state of dysfunction of the endothelium, the cells that line the arteries. Another person confined by COVID-19 has just had a thrombosis in one eye. [...]
Dr. Rodríguez Piedrabuena analyses the effects of confinement on our bodies.
Cortisol has been used during COVID-19 pneumonia because it can slow down the immune system's efforts through a cascade of pro-inflammatory cytokines. Cortisol's main function is to block inflammation caused by any type of damage. Inflammation is inhibited by cortisol in the early stages, [...]