We are not in a position to deny that the confinement, the toxic environment of fragmentation created and maintained every day by some politicians, and their perverse trial balloons, has created stress, and continues to do so - adrenergic stress, because of the adrenalin. Adding this to the multiple insecurities of the citizen as a consequence of the virus. A citizen needs institutional, economic, legal and health stability, all of which are attacked almost daily by the team that governs us. Environmental influences that favour the progression of many tumours, including breast cancer. And other health disorders. To put this in context, CIBERCV researchers at the Centro de Biología Molecular Severo Ochoa have discovered that environmental stress triggers the growth of malignant cells.
The climate of division created and maintained by them and from which they can no longer escape, trapped by their ideology, like Don Quixote, in those endless - at least for me - arguments for their arrogant social engineering. Immune to the facts of reality. All of which is affecting our collective mental health.
All of this can contribute to chronic emotional stress that increases levels of hormones (catecholamines) that act on cancer cells.. These stress hormones increase GRK2 and HuR proteins by activating the production of HIF-1 and blood vessel-forming factors, to nourish the new invading tissues, metastases. These names cannot be disclosed or changed!
By this mechanism, stress may facilitate the survival of malignant cells. Increased levels of these proteins in breast tumours may help them to progress. under conditions of emotional stress, even those same tumours that a priori have better prognosis and treatment as oestrogen-dependent tumours," concludes CIBERCV researcher Petronila Penela. In another article I will explain how this can happen.
The University of Texas MD Anderson Cancer Center has a line of research The project is focused on the field of nutrition, with the collaboration of the oncologist Jennifer McQuade.
A diet rich in vegetables, fruit, olive oil and nuts has been shown to have a great influence on the microbiota, with anti-inflammatory and pro-immune effects (the bacteria in our intestines). It also has a role to play in preventing and improving the effect of treatments once the tumour is established. In a wide range of tumours: in addition to colorectal cancer, other areas of research include melanoma, renal and lung carcinoma.
Dr McQuade says: "These dietary constituents support the colonisation of the bacteria that help digest fibre, because they feed on it and manufacture nutrients for the gut that are essential for the health of our intestinal tissues. Even those about to start immunotherapy and those on a high-fibre diet [regular and high intake of fruit, vegetables and wholegrain cereals, oat flakes] were five times more likely to respond to treatment.
In my book Mediterranean diet and physical exercise, where all this is expanded, I show how a diet rich in fibre (high consumption of vegetables and fruit, whole grains and nuts), beneficial in many other aspects, such as cardiovascular, cholesterol and blood sugar, glycaemia.
Another group of researchers who analysed French patients found that the best response to the inhibitors of checkpoint was associated with the high presence of Akkermansia muciniphilaThe researchers concluded that "the fermentation process produced by the bacteria of those who consume these foods: short-chain fatty acids that are the main nutrient of enterocytes, the cells that make up the mucous layer of the mucous layer of the digestive system. They concluded that "the fermentation process produced by the bacteria of those who consume these foods: short-chain fatty acids are the main nutrient for enterocytes, the cells that make up the mucous layer of the intestine, and that, in turn, contribute to immunity. It has also recently been shown that short-chain fatty acids may be involved in epigenetic changes in the cytotoxic lymphocytes I mentioned in another article and in the conversion of effector T cells into memory cells. So they will expect another attack from the virus and they don't have to learn what it is or how to attack it.
In addition to inadequate gut microbiota and other factors negatively affecting immunity, as I have already written about here: the stress, lack of physical activity, smoking and when they go to bed late or get too little sleep. Too little sleep alters some cellular components of the immune system.
In addition to the above-mentioned diet, it is worth noting a study carried out by researchers from the Faculties of Medicine in Oviedo and Veterinary Medicine at the Complutense University of Madrid.which have shown for the first time in animal models that natural 100% acorn-fed ham has a beneficial effect on certain inflammation-mediated digestive pathologies, such as the case of ulcerative colitis (CU), which adds to the list of health benefits already known about this traditionally cured meat product and one of the mainstays of our Mediterranean diet.
It provides high levels of monounsaturated oleic acid and a low proportion of omega-6 fatty acids and produces important variations in the composition of the intestinal microbiota, promoting the development of several bacterial genera with beneficial anti-inflammatory activity. It also provides high levels of oleic acid and antioxidants. It would be sufficient to ingest 50 grams of this ham daily to get the benefit.
On the possibility of achieving these benefits through supplements, it would not be possible, the bioavailability together with their micronutrients would not be possible with pills.. Eating acorn-fed ham increases actinobacteria, bacteroidetes and proteobacteria. Acorn-fed ham reports very significant changes and increases anti-inflammatory activity in bacterial genera such as alistipes, bacteroides, blautia, butyricimonas and parabacteroides, explains Dr. Felipe Lombó, from the Biotechnology and Bioactive Compounds and Nutraceuticals research group (Bionuc), from the Department of Functional Biology of the Microbiology Area of the University of Barcelona. University of Oviedo.
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José Antonio Rodríguez Piedrabuena
Specialist in psychiatry, management training, group and couple therapies.